本课程精心设计了“药物——把分子送入人体的艺术”、“药物的发现”、“药物的设计”、“药物·生命 ·生活”等四个专题的内容，适合关注医药科学和生命健康的广大人群。课程内容集趣味性、生活性、科学性和前沿性于一身，讲授深入浅出、通俗易懂、趣味盎然，适合普通大众也适合全体大学生。本课程共计1个学分。

    The course has elaborately designed the contents of four topics, such as "drug - the art of delivering molecules into the human body" , "drug discovery" , "drug design" , "drug and life" , and is suitable for people who are interested in medical science and health. Through the systematic study of this course, students can understand and master: What are drugs, how drugs are found and designed reasonably, the relationship between drugs and life, the action mechanism of typical drugs, how to select and use drugs. The content of the course is interesting, lively, scientific and cutting-edge, easy to understand and interesting. This course consists of 16 lectures.

教学特色

1、课程的趣味性。课程将药物历史长河中的名人趣事编成一段段精彩的故事呈现给观众，如诺贝尔与硝酸甘油的百年恩怨、屠呦呦与青蒿素、阿司匹林的前世今生等。

2、课程的科普性。作为公共选修课，力求以通俗易懂的方式普及药物知识，使大众懂得如何在生活中科学识药、用药，如心血管卫士、睡眠与镇静催眠药、有一种痛叫痛风等。教师授课富有激情并不乏幽默，案例简明易懂，与生活联系紧密，采用虚拟蓝箱技术制作，易被各种文化层次的人群理解。

3、课程的前沿性。将世界药物研究的最新成果引入课程，展示药物的奥秘，如抗高血压药物三剑客，高歌猛进——与胃溃疡的斗争，断其后路——替尼类抗癌新药，计算机辅助药物设计。

1. The fun of the course. The course features fascinating stories in the long history of medicine for the audience, such as Nobel and Nitroglycerin, Tu Youyou and Artemisinin, the past and present life of aspirin, and so on.

2. The science popularization of the course. As a public course, it strives to popularize drug knowledge in an easy-to-understand way, so that the public can understand how to scientifically know and use drugs in their daily lives, such as "cardiovascular guardian" , "sleep and sedative hypnotics" , "there is a pain called gout",  etc.

3. The cutting edge of the course. This course introduces the latest advances of medicine research in the world to reveal the secrets of drugs, such as “the three musketeers of antihypertensive drugs”, “the battle against gastric ulcers”, “tinibs new anticancer drugs”, “computer aided drug design”.

课程内容

第一章 药物

1.1 药物——把分子送入人体的艺术

第二章 药物的发现

2.1 奇妙的天然药物

2.2 壮丽的偶然发现

第三章 药物的设计

3.1 抗高血压药物三剑客

3.2 高歌猛进——与胃溃疡的斗争

3.3 断其后路——替尼类抗癌新药

3.4 计算机辅助药物设计

第四章 药物·生命 ·生活

4.1 心血管卫士

4.2 阿司匹林的前世今生

4.3 睡眠与镇静催眠药

4.4 无痛世界——麻醉药

4.5 与疼痛的较量——镇痛药

4.6 抗击流感病毒

4.7 传染病与疫苗

4.8 降血糖药物

4.9 有一种痛叫痛风

Chapter 1 Drug

1.1 Drug -- the art of delivering molecules into the human body

Chapter 2 Drug discovery

2.1 Wonderful natural medicines

2.2 Spectacular serendipity

Chapter 3 Drug design

3.1 The three musketeers of antihypertensive drugs

3.2 The battle against gastric ulcers

3.3 Tinibs new anticancer drugs

3.4 Computer-aided drug design

Chapter 4 Drug and life

4.1 Cardiovascular guardian

4.2 The past and present life of aspirin

4.3 Sleeping and sedative hypnotics

4.4 Anesthetics

4.5 Analgesics

4.6 Fighting the flu virus

4.7 Infectious diseases and vaccines

4.8 Antidiabetic drugs

4.9 There's a pain called gout

通过本课程的系统学习，使学员能够了解和掌握：什么是药物，药物是如何被发现和合理设计的，药物与生命、生活的关系，典型药物的作用机理，如何科学地选择和使用药物等。将慕课和翻转课堂等手段相结合，鼓励学生把自己生活中遇到的药物问题和学习心得上传到平台，与大家一起分享，在理论和实践的结合中一起探索药物的奥秘。

本课程共16讲，采取案例式讲学，每一讲讲授一个专题，按照知识点又分成多个相对独立而又连贯的“节”，每讲视频约15-20分钟。在学生观看教学视频的基础上，我们的助教团队将会充分利用慕课教学平台，调动学生的积极性，建立起活跃的师生互动、生生互动的教学讨论和翻转课堂模式。

《药物的奥秘》（罗华军主编），化学工业出版社，ISBN：9787122351029

其他参考教材